Publications

1.     So NY, Shadlen MN (2022). Decision formation in parietal cortex transcends a fixed frame of reference. Neuron, S0896-6273(22)00664-X. doi: https://doi.org/10.1016/j.neuron.2022.07.019. PMID: 35998631 [PDF] [pubmed]

2.     Stine GM, Trautmann E, Jeurissen D, Shadlen MN (2022).  A neural mechanism for terminating decisions. bioRxiv, doi: https://doi.org/10.1101/2022.05.02.490327 [PDF]

3.     Steinemann N, Stine GM, Trautmann E, Zylberberg A, Wolpert DM, Shadlen MN (2022). Direct observation of the neural computations underlying a single decision. bioRxiv, doi: https://doi.org/10.1101/2022.05.02.490321 [PDF]

4.     Jeurissen D, Shushruth S, El-Shamayleh Y, Horwitz, GD, Shadlen MN (2022).  Deficits in decision-making induced by parietal cortex inactivation are compensated at two timescales.  Neuron, S0896-6273(22)00258-6.  doi: 10.1016/j.neuron.2022.03.022.  PMID: 354213828 [PDF] [pubmed]

5.     Shushruth S, Zylberberg A, Shadlen MN (2022).  Sequential sampling from memory underlies action selection during abstract decision-making. Current Biology, S0960-9822(22)00405-5. Doi: 10.1016/jcub.2022.03.013. PMID: 35354066

6.     Kang YH, Loffler A, Jeurissen D, Zylberberg A, Wolpert DM, Shadlen MN (2021). Multiple Decisions About One Object Involve Parallel Sensory Acquisition but Time-Multiplexed Evidence Incorporation. eLife, vol. 10 e63721. 10 Mar. 2021, doi: 10.7554/eLife.63721. PMCID: PMC8112870

7.     Odean NN, Sanayei M, Shadlen MN (2022).  Transient oscillations of neural firing rate associated with routing of evidence in a perceptual decision. bioRxiv, doi: https://doi.org/10.1101/2022.02.07.478903

8.     Marshall NJ, Glaser JI, Trautmann EM, Amematsro EA, Perkins SM, Shadlen MN, Abbott LF, Cunningham JP, Churchland MM (2021). Flexible neural control of motor units. bioRxiv, doi: https://doi.org/10.1101/2021.05.05.442653

9.     Tremblay, Sébastien et al. “An Open Resource for Non-human Primate Optogenetics.” Neuron vol. 108,6 (2020): 1075-1090.e6. doi:10.1016/j.neuron.2020.09.027. PMCID: PC7962465

10.  Cueva CJ, Saez A, Marcos E, Geovesio A, Jazayeri M, Romo R, Salzman CD, Shadlen MN, Fusi S (2020) Low-dimensional dynamics for working memory and time encoding. ePub, 2020 Sep 15;117(37):23021-23032. doi: 10.1073/pnas.1915984117. PMCID: PMC7502752

11.  Stine GM, Zylberberg A, Ditterich J, Shadlen MN (2020) Differentiating between integration and non-integration strategies in perceptual decision making. Elife 9. PMCID: PMC7217695

12.  Wu Z, Litwin-Kumar A, Shamash P, Taylor A, Axel R, Shadlen MN (2019) Context-dependent decision making in a premotor circuit. Neuron doi: https://doi.org/10.1016/j.neuron.2020.01.034. PMID: 32105611

13.  O’Connell RG, Shadlen MN, Wong-Lin KF, Kelly SP (2018) Bridging Neural and Computational Viewpoints on Perceptual Decision-Making. Trends Neurosci, 41(11): 838-852. PMCID: PMC6215147

14.  Bakkour A, Palombo DJ, Zylberberg A, Kang YH, Reid A, Verfaellie M, Shadlen MN, Shohamy D (2019).  The hippocampus supports deliberation during value based decisions. eLife, 2019;8e46080. PMID: 31268419

15.  Fetsch CR, Odean NN, Jeurissen D, El-Shamayleh Y, Horwitz GD, Shadlen MN (2018). Focal optogenetic suppression in macaque are MT biases direction discrimination and decision confidence, but only transiently. eLife, 2018;7e36523. PMCID: PMC6086666

16.  O’Connell RG, Shadlen MN, Wong-Lin KF, Kelly SP (2018) Bridging Neural and Computational Viewpoints on Perceptual Decision-Making. Trends Neurosci, 14(11):838-852. PMCID: PMC6215147

17.  Zylberberg A, Wolpert DM, Shadlen MN (2018) Counterfactual reasoning underlies the learning of priors in decision making. Neuron 99:1083-1096. PMCID: PMC6127036

18.  Shushruth S, Mazurek M, Shadlen MN (2018). Comparison of decision-related signals in sensory and motor preparatory responses of neurons in Area LIP. J Neurosci 28:6350-6365. PMCID: PMC6041788

19.  Bakkour A, Zylberberg A, Shadlen MN, Shohamy D (2018) Value-based decisions involve sequential sampling from memory. bioRxiv, doi: https://www.biorxiv.org/content/early/2018/02/22/269290

20.  Kang YRH, Petzschner FH, Wolpert DM, Shadlen MN (2017) Piercing of consciousness as a Threshold-Crossing Operation. Curr Biol. 27:1-11. PMCID: PMC5558038

21.  Zylberberg A, Shadlen MN (2016) Cause for pause before leaping to conclusions about stepping. bioRxiv, doi: http://dx.doi.org/10.1101/085886

22.  van den Berg R, Zylberberg, A, Kiani R, Shadlen MN, Wolpert DM (2016) Confidence is the bridge between multi-stage decisions. Curr Biol 26:3157-3168.  PMCID: PMC5154755

23.  Shadlen MN, Shohamy D (2016) Decision making and sequential sampling from memory. Neuron 90:927-939. PMCID: PMC4891701

24.  Zylberberg A, Fetsch CR, Shadlen MN (2016) The influence of evidence volatility on choice, reaction time and confidence in perceptual decision. eLife, 2016;5e17688. PMCID: PMC5083065

25.  Shadlen MN, Kiani R, Newsome WT, Gold JI, Wolpert DM, Zylberberg A, Ditterich J, deLafente V, Yang T, Roitman J (2016) Comment on “Single-trial spike trains in parietal cortex reveal discrete steps during decision-making”. Science, 351:1406. PMCID: PMC6103430

26.  van den Berg R, Anandalingam K, Zylberberg A, Kiani R, Shadlen MN, Wolpert DM (2016) A common mechanism underlies changes of mind about decisions and confidence. eLife, 2016;5:e14790. PMCID: PMC4798971

27.  Jazayeri M, Shadlen MN (2015) A neural mechanism for sensing and reproducing a time interval. Curr Biol, 25:2599-2609. PMCID: PMC4618078

28.  Finnerty GT, Shadlen MN, Jazayeri M, Nobre AC, Buonomano DV (2015) Time in Cortical Circuits. The Journal of Neuroscience: the Official Journal of the Society for Neuroscience, 35(41), 13912–13916. PMCID: PMC4604229

29.  de Lafuente V, Jazayeri M, Shadlen MN (2015) Representation of accumulating evidence for a decision in two parietal areas. J Neurosci 35:4306-4318 PMCID:  PMC4355201

30.  Kira S, Yang T, Shadlen MN (2015) A neural implementation of Wald's sequential probability ratio test. Neuron 85:861-873 PMCID: PMC4365451

31.  Kiani R, Corthell L, Shadlen MN (2014) Choice certainty is informed by both evidence and decision time. Neuron 84:1329-1342. PMCID: PMC4271191

32.  Hanks T, Kiani R, Shadlen MN (2014) A neural mechanism of speed-accuracy tradeoff in macaque area LIP. eLife:e02260. PMCID: PMC4054775

33.  Fetsch CR, Kiani R, Newsome WT, Shadlen MN (2014) Effects of cortical microstimulation on confidence in a perceptual decision. Neuron 83:797-804.  PMCID: PMC4141901

34.  Burk D, Ingram JN, Franklin DW, Shadlen MN, Wolpert DM (2014) Motor effort alters changes of mind in sensorimotor decision making. PLoS ONE 9:e92681.  PMCID: PMC3961398

35.  Kiani R, Churchland AK, Shadlen MN (2013) Integration of direction cues is invariant to the temporal gap between them. J Neuroscience 33:16483-16489.  PMCID: PMC3797371

36.  Cain N, Barreiro A, Shea-Brown E, Shadlen MN (2013) Neural integrators for decision making: A favorable tradeoff between robustness and sensitivity. J Neurophysiol PMCID: PM3653050

37.  Huang Y, Friesen AL, Hanks TD, Shadlen MN, Rao RPN (2012) How prior probability influences decision making:  A unifying probabilistic model. In: Advances in Neural Information Processing Systems: MIT Press. 

38.  Shadlen MN, Roskies AL (2012) The neurobiology of decision-making and responsibility: reconciling mechanism and mindedness. Front Neurosci 6:56.1-12.  PMCID: PMC3332233

39.  Drugowitsch J, Moreno-Bote R, Churchland AK, Shadlen MN, Pouget A (2012) The cost of accumulating evidence in perceptual decision making. J Neurosci 32:3612-3628.  PMCID: PMC3329788

40.  Selen LP, Shadlen MN, Wolpert DM (2012) Deliberation in the motor system: reflex gains track evolving evidence leading to a decision. J Neurosci 32:2276-2286. PMCID: PMC3299561

41.  Hedges JH, Gartshteyn Y, Kohn A, Rust NC, Shadlen MN, Newsome WT, Movshon JA (2011) Dissociation of neuronal and psychophysical responses to local and global motion. Curr Biol 21:2023–2028. PMCID: PMC3241977

42.  Hanks TD, Kiani R, Mazurek M, Hopp E, Shadlen MN (2011) Elapsed decision time affects the weighting of prior probability in a perceptual decision task. J Neurosci 31:6339-52. PMCID: PMC3356114

43.  Churchland AK, Kiani R, Chaudhuri R, Wang XJ, Pouget A, Shadlen MN (2011) Variance as a signature of neural computations during decision-making. Neuron: 69:818-31. PMCID: PMC3066020

44.  Jazayeri M, Shadlen MN (2010). Temporal context calibrates interval timing. Nature Neurosci 13:1020-6. PMCID: PMC2916084

45.  Resulaj A, Kiani R, Wolpert DM, Shadlen MN (2009) Changes of Mind in Decision-Making. Nature 461:263-266. PMCID: PMC2875179

46.  Kiani R, Shadlen MN (2009) Representation of confidence associated with a decision by neurons in the parietal cortex. Science 324:759-764. PMCID: PMC2738936

47.  Kiani R, Hanks TD, Shadlen MN (2008) Bounded integration in parietal cortex underlies decisions even when viewing duration is dictated by the environment. J Neurosci 28:3017-3029. PMID: 18354005

48.  Ganguli S, Bisley JW, Roitman JD, Shadlen MN, Goldberg ME, Miller KD (2008) One-dimensional dynamics of attention and decision making in LIP. Neuron 58:15-25. PMID: 18400159

49.  Churchland AK, Kiani R, Shadlen MN (2008) Decision-making with multiple alternatives. Nat Neurosci 11:693-702. PMCID: PMC2453226

50.  Beck JM, Ma WJ, Kiani R, Hanks T, Churchland AK, Roitman J, Shadlen MN, Latham PE, Pouget A (2008) Probabilistic population codes for Bayesian decision making. Neuron 60:1142-1152. PMID: 19109917

51.  Gold JI, Shadlen MN (2007) The Neural Basis of Decision Making. Annu Rev Neurosci 30:535-574. PMID: 17600525

52.  Yang T, Shadlen MN (2007) Probabilistic reasoning by neurons. Nature 447:1075-1080. PMID: 17546027

53.  Wong KF, Huk AC, Shadlen MN, Wang XJ (2007) Neural circuit dynamics underlying accumulation of time-varying evidence during decision-making. Frontiers in Computational Neurosci 1:1-11. PMCID: PMC2525934

54.  Hanks TD, Ditterich J, Shadlen MN (2006) Microstimulation of macaque area LIP affects decision-making in a motion discrimination task. Nat Neurosci 9:682 - 689. PMCID: PMC2770004

55.  Palmer J, Huk AC, Shadlen MN (2005) The effect of stimulus strength on the speed and accuracy of a perceptual decision. Journal of Vision 5:376-404. PMID: 16097871

56.  Janssen P, Shadlen MN (2005) A representation of the hazard rate of elapsed time in macaque area LIP. Nat Neurosci 8:234-241. PMID: 15657597

57.  Huk AC, Shadlen MN (2005) Neural activity in macaque parietal cortex reflects temporal integration of visual motion signals during perceptual decision making. J Neurosci 25:10420-10436. PMID: 16280581

58.  Mazurek ME, Roitman JD, Ditterich J, Shadlen MN (2003) A role for neural integrators in perceptual decision making. Cereb Cortex 13:1257-1269. PMID: 14576217

59.  Leon MI, Shadlen MN (2003) Representation of time by neurons in the posterior parietal cortex of the macaque. Neuron 38:317-327. PMID: 12718864

60.  Gold JI, Shadlen MN (2003) The influence of behavioral context on the representation of a perceptual decision in developing oculomotor commands. J Neurosci 23:632-651. PMID: 12533623

61.  Ditterich J, Mazurek M, Shadlen MN (2003) Microstimulation of visual cortex affects the speed of perceptual decisions. Nat Neurosci 6:891-898. PMID: 12858179

62.  Roitman JD, Shadlen MN (2002) Response of neurons in the lateral intraparietal area during a combined visual discrimination reaction time task. J Neurosci 22:9475-9489. PMID: 12417672

63.  Mazurek ME, Shadlen MN (2002) Limits to the temporal fidelity of cortical spike rate signals. Nat Neurosci 5:463-471. PMID: 11976706

64.  Gold JI, Shadlen MN (2002) Banburismus and the brain: decoding the relationship between sensory stimuli, decisions, and reward. Neuron 36:299-308. PMID: 12383783

65.  Shadlen MN, Newsome WT (2001) Neural basis of a perceptual decision in the parietal cortex (area LIP) of the rhesus monkey. J Neurophysiol 86:1916-1936. PMID: 11600651

66.  Gold JI, Shadlen MN (2001) Neural computations that underlie decisions about sensory stimuli. Trends Cogn Sci 5:10-16. PMID: 11164731

67.  Gold JI, Shadlen MN (2000) Representation of a perceptual decision in developing oculomotor commands. Nature 404:390-394. PMID: 10746726

68.  Leon MI, Shadlen MN (1999) Effect of expected reward magnitude on the response of neurons in the dorsolateral prefrontal cortex of the macaque. Neuron 24:415-425. PMID: 10571234

69.  Kim JN, Shadlen MN (1999) Neural correlates of a decision in the dorsolateral prefrontal cortex of the macaque. Nat Neurosci 2:176-185. PMID: 10195203

70.  Shadlen MN, Newsome WT (1998) The variable discharge of cortical neurons: implications for connectivity, computation and information coding. J Neurosci 18:3870-3896. PMID: 9570816

71.  Olshen RA, Shadlen MN (1997) Discussion of "Non-linear Fourier time series analysis for human brain mapping" by N. Lange and S.L. Zeger. Journal of the Royal Statistical Society (Series C) 46:22.

72.  Shadlen MN, Newsome WT (1996) Motion perception: seeing and deciding. Proc Natl Acad Sci (USA) 93:628-633. PMCID: PMC40102

73.  Shadlen MN, Britten KH, Newsome WT, Movshon JA (1996) A computational analysis of the relationship between neuronal and behavioral responses to visual motion. J Neurosci 16:1486-1510. PMID: 8778300

74.  Britten KH, Newsome WT, Shadlen MN, Celebrini S, Movshon JA (1996) A relationship between behavioral choice and the visual responses of neurons in macaque MT. Visual Neurosci 13:87-100. PMID: 8730992

75.  Zohary E, Shadlen MN, Newsome WT (1994) Correlated neuronal discharge rate and its implications for psychophysical performance. Nature 370:140-143. PMID: 8022482

76.  Shadlen MN, Newsome WT (1994) Noise, neural codes and cortical organization. Curr Opin Neurobiol 4:569-579. PMID: 7812147

77.  Engel S, Rumelhart D, Wandell B, Lee A, Glover G, Chichilnisky E, Shadlen M (1994) fMRI of human visual cortex. Nature 369:525. PMID: 8031403

78.  Carney T, Shadlen MN (1993) Dichoptic activation of the early motion system. Vision Res 33:1977-1995. PMID: 8249314

79.  Britten KH, Shadlen MN, Newsome WT, Movshon JA (1993) Responses of neurons in macaque MT to stochastic motion signals. Vis Neurosci 10:1157-1169. PMID: 8257671

80.  Britten KH, Shadlen MN, Newsome WT, Movshon JA (1992) The analysis of visual motion: a comparison of neuronal and psychophysical performance. J Neurosci 12:4745-4765. PMID: 1464765

81.  Ramoa AS, Shadlen MN, Freeman RD (1987) Dark-reared cats: Unresponsive cells become visually responsive with micro-iontophoresis of an excitatory amino acid. Exp Brain Res 65:658-665. PMID: 3556492

82.  Carney T, Shadlen M, Switkes E (1987) Parallel processing of motion and colour information. Nature 328:647-649. PMID: 3614368

83.  Shadlen M, Carney T (1986) Mechanisms of human motion perception revealed by a new cyclopean illusion. Science 232:95-97. PMID: 3952502

84.  Ramoa AS, Shadlen MN, Skottun BC, Freeman RD (1986) A comparison of inhibition in orientation and spatial frequency selectivity of cat visual cortex. Nature 321:237-239. PMID: 3713805

 

REVIEWS, CHAPTERS, EDITORIALS:

  1. Shadlen MN, Kandel ER (2021) Decision-Making and Consciousness in Principles of Neural Science, 6th Edition, (Ed. Kandel ER, Koester JD, Mack SH, Siegelbaum SA), McGraw Hill, New York.

  2. Shadlen MN, Kandel ER (2021) The Brain and Behavior in Principles of Neural Science, 6th Edition, (Ed. Kandel ER, Koester JD, Mack SH, Siegelbaum SA), McGraw Hill, New York.

  3. Shadlen MN, Kandel ER (2021) Nerve Cells, Neural Circuitry, and Behavior in Principles of Neural Science, 6th Edition, (Ed. Kandel ER, Koester JD, Mack SH, Siegelbaum SA), McGraw Hill, New York.

  4. Bayne T, Brainard D, Byrne RW, Chittka L, Clayton N, Heyes C, Mather J, Ölveczky B, Shadlen MN, Suddendorf T, Webb B (2019). What is cognition?. Current Biology, 29(13), R608-R615.

  5. Shadlen MN (2014) Can neuroscience resolve issues about free will. In: Moral Psychology, Free will and Moral Responsibility, Volume 4. (Sinnott-Armstrong W, ed): MIT Press.

  6. Shadlen MN, Kiani R (2013) Decision making as a window on cognition. Neuron 80(3): 791-806. PMCID: PMC3852636

  7. Doya K, Shadlen MN (2012) Decision making. Current Opinion in Neurobiology. 22:911-913. PMID: 23177659

  8. Shadlen MN, Kiani R (2011) Consciousness as a decision to engage. In: Characterizing Consciousness: From Cognition to the Clinic? Research and Perspectives in Neurosciences. (Dehaene S, Christen Y, eds), pp 27-46. Berlin Heidelberg: Springer-Verlag

  9. Shadlen MN, Kiani R, Hanks TD, Churchland AK (2008) Neurobiology of Decision Making. An Intentional Framework. In: Strüngmann Forum Report: Better Than Conscious? Implications for Performance and Institutional Analysis (Engel C, Singer W, eds).

  10. Shadlen MN, Kiani R (2007) Neurology: an awakening. Nature 448:539-540.

  11. Kiani R, Hanks TD, Shadlen MN (2006) When is enough enough? Nat Neurosci 9:861-863.

  12. Shadlen MN, Hanks TD, Churchland AK, Kiani R, Yang T (2006) The speed and accuracy of a simple perceptual decision: a mathematical primer. In: Bayesian Brain: Probabilistic Approaches to Neural Coding. (Doya K, Ishii S, Rao R, Pouget A, eds), pp 209-237. Cambridge: MIT Press.

  13. Shadlen MN, Gold JI (2004) The neurophysiology of decision-making as a window on cognition. In: The Cognitive Neurosciences, 3rd edition. (Gazzaniga MS, ed): MIT Press.

  14. Shadlen MN (2002) Rate versus temporal coding of information in cerebral cortex. In: Encyclopedia of Cognitive Science: Macmillan.

  15. Shadlen MN (2002) Pursuing commitments. Nat Neurosci 5:819-821.

  16. Shadlen MN, Movshon JA (1999) Synchrony unbound: a critical evaluation of the temporal binding hypothesis. Neuron 24:67-77.

  17. Leon MI, Shadlen MN (1998) Exploring the neurophysiology of decisions. Neuron 21:669-672.

  18. Shadlen MN (1997) Look but don't touch, or vice versa. Nature 386:122-123.

  19. Shadlen MN, Newsome WT (1995) Is there a signal in the noise? Curr Opin Neurobiol 5:248-250.

  20. Newsome WT, Shadlen MN, Zohary E, Britten KH, Movshon JA (1995) Visual motion: linking neuronal activity to psychophysical performance. In: The Cognitive Neurosciences (Gazzaniga M, ed), pp 401-414. Cambridge, Mass: MIT Press.

  21. Carney T, Shadlen MN (1992) Binocularity of early motion mechanisms: comments on Georgeson and Shackleton. Vision Res 32:187-191.

  22. Newsome WT, Britten KH, Movshon JA, Shadlen M (1989) Single neurons and the perception of visual motion. In: Neural mechanisms of visual perception. Proceedings of the retina research foundation. (Lam DM-K, Gilbert CD, eds), pp 171-198. The Woodlands, TX: Portfolio Publishing Company.

  23. Shadlen, MN (1982). Refugees of El Salvador: a firsthand account of their precarious health and safety. The New Physician 5:24-29.